simple linear regression equation on phstat

By contrast, there was no difference between the pH-stat shunt animals and either control group (2.1 ± 0.2 vs 2.3 ± 0.2 and 2.0 ± 0.3 ml oxygen per 100 gm/min, p = not significant).

The cerebral metabolic rate of oxygen consumption (a marker for neurologic function) was significantly lower after circulatory arrest in the shunt animals cooled with alpha-stat blood gas management than in the control animals subjected to alpha-stat management (1.2 ± 0.2 vs 2.3 ± 0.2 ml oxygen per 100 gm/min, p < 0.05). All animals were supported with cardiopulmonary bypass, cooled to 18º C by means of either alpha-stat (five control and five shunt animals) or pH-stat (five control and five shunt animals) blood gas management, subjected to circulatory arrest for 90 minutes, and rewarmed to 37º C. In control animals ( n = 10) the shunts were immediately ligated, whereas in the shunt animals ( n = 10) the shunts were left patent. Twenty 4- to 6-week-old piglets underwent placement of a shunt between the left subclavian artery and main pulmonary artery. The current study was designed to test whether cooling with pH-stat blood gas management can decrease the cerebral metabolic impact of aortopulmonary collaterals. Use of pH-stat blood gas management has been shown to increase cerebral blood flow during cooling. Experimental studies have demonstrated that such collaterals decrease the rate of cerebral cooling before arrest and cerebral metabolic recovery after circulatory arrest. Cardiopulmonary bypass with deep hypothermic circulatory arrest increases the risk of neurologic injury in patients with aortopulmonary collaterals.

Simple linear regression equation on phstat